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NF-κB repressing factor downregulates basal expression and mycobacterium tuberculosis induced IP-10 and IL-8 synthesis via interference with NF-κB in monocytes

BACKGROUND: Our previous study showed NF-κB repressing factor (NKRF) downregulates IP-10 and IL-8 synthesis in the peripheral blood mononuclear cells and alveolar macrophages of TB patients with high bacterial loads. However, the mechanism underlying the repressive effect of NKRF is not fully unders...

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Detalles Bibliográficos
Autores principales:	Huang, Kuo-Hsiung, Wang, Chun-Hua, Lin, Chien-Huang, Kuo, Han-Pin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237804/ https://www.ncbi.nlm.nih.gov/pubmed/25135111 http://dx.doi.org/10.1186/s12929-014-0071-5

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