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Antitumor effect of therapeutic HPV DNA vaccines with chitosan-based nanodelivery systems
BACKGROUND: Cervical cancer is the second-most-common cause of malignancies in women worldwide, and the oncogenic activity of the human papilloma virus types (HPV) E7 protein has a crucial role in anogenital tumors. In this study, we have designed a therapeutic vaccine based on chitosan nanodelivery...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237815/ https://www.ncbi.nlm.nih.gov/pubmed/25077570 http://dx.doi.org/10.1186/s12929-014-0069-z |