Promoter methylation analysis of WNT/β-catenin pathway regulators and its association with expression of DNMT1 enzyme in colorectal cancer

BACKGROUND: Aberrant DNA methylation as the most important reason making epigenetic silencing of genes is a main mechanism of gene inactivation in patients with colorectal cancer. In this study, we decided to identify promoter methylation status of ten genes encoding WNT negative regulators, and mea...

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Detalles Bibliográficos
Autores principales: Samaei, Nader Mansour, Yazdani, Yaghoub, Alizadeh-Navaei, Reza, Azadeh, Hossein, Farazmandfar, Touraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237828/
https://www.ncbi.nlm.nih.gov/pubmed/25107489
http://dx.doi.org/10.1186/s12929-014-0073-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237828/
https://www.ncbi.nlm.nih.gov/pubmed/25107489
http://dx.doi.org/10.1186/s12929-014-0073-3

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