Cargando…
The role of telomeres and telomerase in hematologic malignancies and hematopoietic stem cell transplantation
Telomeres are specific nucleoprotein structures at the ends of eukaryotic chromosomes. Telomeres and telomere-associated proteins maintain genome stability by protecting the ends of chromosomes from fusion and degradation. In normal somatic cells, the length of the telomeres gradually becomes shorte...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237881/ https://www.ncbi.nlm.nih.gov/pubmed/25139287 http://dx.doi.org/10.1186/s13045-014-0061-9 |