Interferon regulatory factor (IRF) 3 is critical for the development of experimental autoimmune encephalomyelitis

BACKGROUND: Experimental autoimmune encephalomyelitis (EAE) is an animal model of autoimmune inflammatory demyelination that is mediated by Th1 and Th17 cells. The transcription factor interferon regulatory factor 3 (IRF3) is activated by pathogen recognition receptors and induces interferon-β produ...

Descripción completa

Detalles Bibliográficos
Autores principales: Fitzgerald, Denise C, O’Brien, Kate, Young, Andrew, Fonseca-Kelly, Zoe, Rostami, Abdolmohamad, Gran, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237888/
https://www.ncbi.nlm.nih.gov/pubmed/25069698
http://dx.doi.org/10.1186/1742-2094-11-130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237888/
https://www.ncbi.nlm.nih.gov/pubmed/25069698
http://dx.doi.org/10.1186/1742-2094-11-130

Ejemplares similares