Cargando…

TLR4 enhances histamine-mediated pruritus by potentiating TRPV1 activity

BACKGROUND: Recent studies have indicated that Toll-like receptor 4 (TLR4), a pathogen-recognition receptor that triggers inflammatory signals in innate immune cells, is also expressed on sensory neurons, implicating its putative role in sensory signal transmission. However, the possible function of...

Descripción completa

Detalles Bibliográficos
Autores principales: Min, Hyunjung, Lee, Hyunkyoung, Lim, Hyoungsub, Jang, Yong Ho, Chung, Sung Jun, Lee, C Justin, Lee, Sung Joong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237911/
https://www.ncbi.nlm.nih.gov/pubmed/25139109
http://dx.doi.org/10.1186/s13041-014-0059-9