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TLR4 enhances histamine-mediated pruritus by potentiating TRPV1 activity
BACKGROUND: Recent studies have indicated that Toll-like receptor 4 (TLR4), a pathogen-recognition receptor that triggers inflammatory signals in innate immune cells, is also expressed on sensory neurons, implicating its putative role in sensory signal transmission. However, the possible function of...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237911/ https://www.ncbi.nlm.nih.gov/pubmed/25139109 http://dx.doi.org/10.1186/s13041-014-0059-9 |