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Mechanism-based genotoxicity screening of metal oxide nanoparticles using the ToxTracker panel of reporter cell lines

BACKGROUND: The rapid expansion of manufacturing and use of nano-sized materials fuels the demand for fast and reliable assays to identify their potential hazardous properties and underlying mechanisms. The ToxTracker assay is a recently developed mechanism-based reporter assay based on mouse embryo...

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Detalles Bibliográficos
Autores principales: Karlsson, Hanna L, Gliga, Anda R, Calléja, Fabienne MGR, Gonçalves, Cátia SAG, Wallinder, Inger Odnevall, Vrieling, Harry, Fadeel, Bengt, Hendriks, Giel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237954/
https://www.ncbi.nlm.nih.gov/pubmed/25179117
http://dx.doi.org/10.1186/s12989-014-0041-9