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Bayesian approach for the estimation of cyclosporine area under the curve using limited sampling strategies in pediatric hematopoietic stem cell transplantation

BACKGROUND: The optimal marker for cyclosporine (CsA) monitoring in transplantation patients remains controversial. However, there is a growing interest in the use of the area under the concentration-time curve (AUC), particularly for cyclosporine dose adjustment in pediatric hematopoietic stem cell...

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Detalles Bibliográficos
Autores principales: Sarem, Sarem, Li, Jun, Barriere, Olivier, Litalien, Catherine, Théorêt, Yves, Lapeyraque, Anne-Laure, Nekka, Fahima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237955/
https://www.ncbi.nlm.nih.gov/pubmed/25192585
http://dx.doi.org/10.1186/1742-4682-11-39