Abnormalities in the zinc-metalloprotease-BDNF axis may contribute to megalencephaly and cortical hyperconnectivity in young autism spectrum disorder patients

Whereas aberrant brain connectivity is likely the core pathology of autism-spectrum disorder (ASD), studies do not agree as to whether hypo- or hyper-connectivity is the main underlying problem. Recent functional imaging studies have shown that, in most young ASD patients, cerebral cortical regions...

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Detalles Bibliográficos
Autores principales: Koh, Jae-Young, Lim, Joon Seo, Byun, Hyae-Ran, Yoo, Min-Heui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237964/
https://www.ncbi.nlm.nih.gov/pubmed/25182223
http://dx.doi.org/10.1186/s13041-014-0064-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237964/
https://www.ncbi.nlm.nih.gov/pubmed/25182223
http://dx.doi.org/10.1186/s13041-014-0064-z

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