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Tissue-specific regulation of pregnane X receptor in cancer development and therapy

As a ligand-dependent transcription factor of the nuclear hormone receptor superfamily, the pregnane X receptor (PXR) has a multitude of functions including regulating xenobiotic and cholesterol metabolism, energy homeostasis, gut mucosal defense, and cancer development. Whereas the detoxification f...

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Detalles Bibliográficos
Autores principales: Robbins, Delira, Chen, Taosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237984/
https://www.ncbi.nlm.nih.gov/pubmed/24690092
http://dx.doi.org/10.1186/2045-3701-4-17