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Tissue-specific regulation of pregnane X receptor in cancer development and therapy
As a ligand-dependent transcription factor of the nuclear hormone receptor superfamily, the pregnane X receptor (PXR) has a multitude of functions including regulating xenobiotic and cholesterol metabolism, energy homeostasis, gut mucosal defense, and cancer development. Whereas the detoxification f...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4237984/ https://www.ncbi.nlm.nih.gov/pubmed/24690092 http://dx.doi.org/10.1186/2045-3701-4-17 |