Stochastic promoter activation affects Nanog expression variability in mouse embryonic stem cells

Mouse embryonic stem cells (mESCs) are self-renewing and capable of differentiating into any of the three germ layers. An interesting feature of mESCs is the presence of cell-to-cell heterogeneity in gene expression that may be responsible for cell fate decisions. Nanog, a key transcription factor f...

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Detalles Bibliográficos
Autores principales: Ochiai, Hiroshi, Sugawara, Takeshi, Sakuma, Tetsushi, Yamamoto, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238020/
https://www.ncbi.nlm.nih.gov/pubmed/25410303
http://dx.doi.org/10.1038/srep07125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238020/
https://www.ncbi.nlm.nih.gov/pubmed/25410303
http://dx.doi.org/10.1038/srep07125

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