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ARGONAUTE PIWI domain and microRNA duplex structure regulate small RNA sorting in Arabidopsis

Small RNAs (sRNAs) are loaded into ARGONAUTE (AGO) proteins to induce gene silencing. In plants, the 5′-terminal nucleotide is important for sRNA sorting into different AGOs. Here, we show that miRNA duplex structure also contributes to miRNA sorting. Base-pairing at the 15(th) nucleotide of a miRNA...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoming, Niu, DongDong, Carbonell, Alberto, Wang, Airong, Lee, Angel, Tun, Vinnary, Wang, Zonghua, Carrington, James C., Chang, Chia-en A., Jin, Hailing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238042/
https://www.ncbi.nlm.nih.gov/pubmed/25406978
http://dx.doi.org/10.1038/ncomms6468