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Diverse modes of evolutionary emergence and flux of conserved microRNA clusters

Many animal miRNA loci reside in genomic clusters that generate multicistronic primary-miRNA transcripts. While clusters that contain copies of the same miRNA hairpin are clearly products of local duplications, the evolutionary provenance of clusters with disparate members is less clear. Recently, i...

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Detalles Bibliográficos
Autores principales: Mohammed, Jaaved, Siepel, Adam, Lai, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238352/
https://www.ncbi.nlm.nih.gov/pubmed/25332374
http://dx.doi.org/10.1261/rna.046805.114