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Structural insights into translational recoding by frameshift suppressor tRNA(SufJ)

The three-nucleotide mRNA reading frame is tightly regulated during translation to ensure accurate protein expression. Translation errors that lead to aberrant protein production can result from the uncoupled movement of the tRNA in either the 5′ or 3′ direction on mRNA. Here, we report the biochemi...

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Detalles Bibliográficos
Autores principales: Fagan, Crystal E., Maehigashi, Tatsuya, Dunkle, Jack A., Miles, Stacey J., Dunham, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238358/
https://www.ncbi.nlm.nih.gov/pubmed/25352689
http://dx.doi.org/10.1261/rna.046953.114