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Crystal structure of a signal recognition particle Alu domain in the elongation arrest conformation

The signal recognition particle (SRP) is a conserved ribonucleoprotein particle that targets membrane and secreted proteins to translocation channels in membranes. In eukaryotes, the Alu domain, which comprises the 5′ and 3′ extremities of the SRP RNA bound to the SRP9/14 heterodimer, is thought to...

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Detalles Bibliográficos
Autores principales: Bousset, Luc, Mary, Camille, Brooks, Mark A., Scherrer, Anne, Strub, Katharina, Cusack, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238359/
https://www.ncbi.nlm.nih.gov/pubmed/25336584
http://dx.doi.org/10.1261/rna.047209.114