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IDO2 in Immunomodulation and Autoimmune Disease

IDO2 is a relative of IDO1 implicated in tryptophan catabolism and immune modulation but its specific contributions to normal physiology and pathophysiology are not known. Evolutionary genetic studies suggest that IDO2 has a unique function ancestral to IDO1. In mice, IDO2 gene deletion does not app...

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Detalles Bibliográficos
Autores principales: Prendergast, George C., Metz, Richard, Muller, Alexander J., Merlo, Lauren M. F., Mandik-Nayak, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238401/
https://www.ncbi.nlm.nih.gov/pubmed/25477879
http://dx.doi.org/10.3389/fimmu.2014.00585