G protein-coupled receptor kinase 2 moderates recruitment of THP-1 cells to the endothelium by limiting histamine-invoked Weibel-Palade body exocytosis

BACKGROUND: G protein-coupled receptors (GPCRs) are a major family of signaling molecules, central to the regulation of inflammatory responses. Their activation upon agonist binding is attenuated by GPCR kinases (GRKs), which desensitize the receptors through phosphorylation. G protein-coupled recep...

Descripción completa

Detalles Bibliográficos
Autores principales: Stevenson, N L, Martin-Martin, B, Freeman, J, Kriston-Vizi, J, Ketteler, R, Cutler, D F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Vascular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238739/
https://www.ncbi.nlm.nih.gov/pubmed/24735118
http://dx.doi.org/10.1111/jth.12470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238739/
https://www.ncbi.nlm.nih.gov/pubmed/24735118
http://dx.doi.org/10.1111/jth.12470

Ejemplares similares