Cargando…

JVG9, a benzimidazole derivative, alters the surface and cytoskeleton of Trypanosoma cruzi bloodstream trypomastigotes

Trypanosoma cruzi has a particular cytoskeleton that consists of a subpellicular network of microtubules and actin microfilaments. Therefore, it is an excellent target for the development of new anti-parasitic drugs. Benzimidazole 2-carbamates, a class of well-known broad-spectrum anthelmintics, hav...

Descripción completa

Detalles Bibliográficos
Autores principales: Díaz-Chiguer, Dylan L, Hernández-Luis, Francisco, Nogueda-Torres, Benjamín, Castillo, Rafael, Reynoso-Ducoing, Olivia, Hernández-Campos, Alicia, Ambrosio, Javier R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238767/
https://www.ncbi.nlm.nih.gov/pubmed/25317703
http://dx.doi.org/10.1590/0074-0276140096