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Culture of mouse peritoneal macrophages with mouse serum induces lipid bodies that associate with the parasitophorous vacuole and decrease their microbicidal capacity against Toxoplasma gondii

Lipid bodies [lipid droplets (LBs)] are lipid-rich organelles involved in lipid metabolism, signalling and inflammation. Recent findings suggest a role for LBs in host response to infection; however, the potential functions of this organelle in Toxoplasma gondii infection and how it alters macrophag...

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Detalles Bibliográficos
Autores principales: Mota, Laura Azeredo Miranda, Roberto, João, Monteiro, Verônica Gomes, Lobato, Caroliny Samary Silva, de Oliveira, Marco Antonio, da Cunha, Maura, D’Ávila, Heloisa, Seabra, Sérgio Henrique, Bozza, Patrícia Torres, DaMatta, Renato Augusto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238769/
https://www.ncbi.nlm.nih.gov/pubmed/25317704
http://dx.doi.org/10.1590/0074-0276140119