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Alpha-synuclein mRNA expression in oligodendrocytes in MSA

Multiple system atrophy (MSA) is a progressive neurodegenerative disease presenting clinically with parkinsonian, cerebellar, and autonomic features. α-Synuclein (αsyn), encoded by the gene SNCA, is the main constituent of glial cytoplasmic inclusion (GCI) found in oligodendrocytes in MSA, but the m...

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Detalles Bibliográficos
Autores principales: Asi, Yasmine T, Simpson, Julie E, Heath, Paul R, Wharton, Stephen B, Lees, Andrew J, Revesz, Tamas, Houlden, Henry, Holton, Janice L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238782/
https://www.ncbi.nlm.nih.gov/pubmed/24590631
http://dx.doi.org/10.1002/glia.22653