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Amplification of human platelet activation by surface pannexin-1 channels

BACKGROUND: Pannexin-1 (Panx1) forms an anion-selective channel with a permeability up to ∼1 kDa and represents a non-lytic, non-vesicular ATP release pathway in erythrocytes, leukocytes and neurons. Related connexin gap junction proteins have been reported in platelets; however, the expression and...

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Detalles Bibliográficos
Autores principales: Taylor, K A, Wright, J R, Vial, C, Evans, R J, Mahaut-Smith, M P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238786/
https://www.ncbi.nlm.nih.gov/pubmed/24655807
http://dx.doi.org/10.1111/jth.12566