Cargando…
Mutations in the Proteolipid Subunits of the Vacuolar H(+)-ATPase Provide Resistance to Indolotryptoline Natural Products
[Image: see text] Indolotryptoline natural products represent a small family of structurally unique chromopyrrolic acid-derived antiproliferative agents. Like many prospective anticancer agents before them, the exploration of their potential clinical utility has been hindered by the limited informat...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238801/ https://www.ncbi.nlm.nih.gov/pubmed/25319670 http://dx.doi.org/10.1021/bi501078j |