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Mutations in the Proteolipid Subunits of the Vacuolar H(+)-ATPase Provide Resistance to Indolotryptoline Natural Products

[Image: see text] Indolotryptoline natural products represent a small family of structurally unique chromopyrrolic acid-derived antiproliferative agents. Like many prospective anticancer agents before them, the exploration of their potential clinical utility has been hindered by the limited informat...

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Detalles Bibliográficos
Autores principales:	Chang, Fang-Yuan, Kawashima, Shigehiro A., Brady, Sean F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238801/ https://www.ncbi.nlm.nih.gov/pubmed/25319670 http://dx.doi.org/10.1021/bi501078j

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