Immunologic checkpoints in cancer therapy: focus on the programmed death-1 (PD-1) receptor pathway

T-lymphocytes have the potential to recognize cancer antigens as foreign and therefore eliminate them. However, immune checkpoints such as cytotoxic T-lymphocyte-associated antigen (CTLA)-4 and programmed cell death (PD)-1 receptor and its ligands (PD-L1, PD-L2) suppress the activity of T-lymphocyte...

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Detalles Bibliográficos
Autores principales: Momtaz, Parisa, Postow, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238865/
https://www.ncbi.nlm.nih.gov/pubmed/25484597
http://dx.doi.org/10.2147/PGPM.S53163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238865/
https://www.ncbi.nlm.nih.gov/pubmed/25484597
http://dx.doi.org/10.2147/PGPM.S53163

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