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Quantitative Genetics of CTCF Binding Reveal Local Sequence Effects and Different Modes of X-Chromosome Association

Associating genetic variation with quantitative measures of gene regulation offers a way to bridge the gap between genotype and complex phenotypes. In order to identify quantitative trait loci (QTLs) that influence the binding of a transcription factor in humans, we measured binding of the multifunc...

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Detalles Bibliográficos
Autores principales: Ding, Zhihao, Ni, Yunyun, Timmer, Sander W., Lee, Bum-Kyu, Battenhouse, Anna, Louzada, Sandra, Yang, Fengtang, Dunham, Ian, Crawford, Gregory E., Lieb, Jason D., Durbin, Richard, Iyer, Vishwanath R., Birney, Ewan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238955/
https://www.ncbi.nlm.nih.gov/pubmed/25411781
http://dx.doi.org/10.1371/journal.pgen.1004798