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Quantitative Genetics of CTCF Binding Reveal Local Sequence Effects and Different Modes of X-Chromosome Association
Associating genetic variation with quantitative measures of gene regulation offers a way to bridge the gap between genotype and complex phenotypes. In order to identify quantitative trait loci (QTLs) that influence the binding of a transcription factor in humans, we measured binding of the multifunc...
Autores principales: | Ding, Zhihao, Ni, Yunyun, Timmer, Sander W., Lee, Bum-Kyu, Battenhouse, Anna, Louzada, Sandra, Yang, Fengtang, Dunham, Ian, Crawford, Gregory E., Lieb, Jason D., Durbin, Richard, Iyer, Vishwanath R., Birney, Ewan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238955/ https://www.ncbi.nlm.nih.gov/pubmed/25411781 http://dx.doi.org/10.1371/journal.pgen.1004798 |
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