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Estimating Relative Changes of Metabolic Fluxes

Fluxes are the central trait of metabolism and Kinetic Flux Profiling (KFP) is an effective method of measuring them. To generalize its applicability, we present an extension of the method that estimates the relative changes of fluxes using only relative quantitation of (13)C-labeled metabolites. Su...

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Detalles Bibliográficos
Autores principales: Huang, Lei, Kim, Dongsung, Liu, Xiaojing, Myers, Christopher R., Locasale, Jason W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238958/
https://www.ncbi.nlm.nih.gov/pubmed/25412287
http://dx.doi.org/10.1371/journal.pcbi.1003958