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Pathophysiologic and Transcriptomic Analyses of Viscerotropic Yellow Fever in a Rhesus Macaque Model

Infection with yellow fever virus (YFV), an explosively replicating flavivirus, results in viral hemorrhagic disease characterized by cardiovascular shock and multi-organ failure. Unvaccinated populations experience 20 to 50% fatality. Few studies have examined the pathophysiological changes that oc...

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Detalles Bibliográficos
Autores principales: Engelmann, Flora, Josset, Laurence, Girke, Thomas, Park, Byung, Barron, Alex, Dewane, Jesse, Hammarlund, Erika, Lewis, Anne, Axthelm, Michael K., Slifka, Mark K., Messaoudi, Ilhem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238990/
https://www.ncbi.nlm.nih.gov/pubmed/25412185
http://dx.doi.org/10.1371/journal.pntd.0003295