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CD8(+) T cells Are Preferentially Activated during Primary Low Dose Leishmania major Infection but Are Completely Dispensable during Secondary Anti-Leishmania Immunity

We previously showed that CD8(+) T cells are required for optimal primary immunity to low dose Leishmania major infection. However, it is not known whether immunity induced by low dose infection is durable and whether CD8(+) T cells contribute to secondary immunity following recovery from low dose i...

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Detalles Bibliográficos
Autores principales: Okwor, Ifeoma B., Jia, Ping, Mou, Zhirong, Onyilagha, Chukwunonso, Uzonna, Jude E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238992/
https://www.ncbi.nlm.nih.gov/pubmed/25412267
http://dx.doi.org/10.1371/journal.pntd.0003300