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Indoleamine 2,3-Dioxygenase Controls Fungal Loads and Immunity in Paracoccidioidomicosis but is More Important to Susceptible than Resistant Hosts

BACKGROUND: Paracoccidioidomycosis, a primary fungal infection restricted to Latin America, is acquired by inhalation of fungal particles. The immunoregulatory mechanisms that control the severe and mild forms of paracoccidioidomycosis are still unclear. Indoleamine 2,3-dioxygenase (IDO), an IFN-γ i...

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Detalles Bibliográficos
Autores principales: Araújo, Eliseu F., Loures, Flávio V., Bazan, Silvia B., Feriotti, Claudia, Pina, Adriana, Schanoski, Alessandra S., Costa, Tânia A., Calich, Vera L. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238999/
https://www.ncbi.nlm.nih.gov/pubmed/25411790
http://dx.doi.org/10.1371/journal.pntd.0003330