Fingolimod Increases CD39-Expressing Regulatory T Cells in Multiple Sclerosis Patients

BACKGROUND: Multiple sclerosis (MS) likely results from an imbalance between regulatory and inflammatory immune processes. CD39 is an ectoenzyme that cleaves ATP to AMP and has been suggested as a novel regulatory T cells (Treg) marker. As ATP has numerous proinflammatory effects, its degradation by...

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Detalles Bibliográficos
Autores principales: Muls, Nathalie, Dang, Hong Anh, Sindic, Christian J. M., van Pesch, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239031/
https://www.ncbi.nlm.nih.gov/pubmed/25411844
http://dx.doi.org/10.1371/journal.pone.0113025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239031/
https://www.ncbi.nlm.nih.gov/pubmed/25411844
http://dx.doi.org/10.1371/journal.pone.0113025

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