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Fingolimod Increases CD39-Expressing Regulatory T Cells in Multiple Sclerosis Patients
BACKGROUND: Multiple sclerosis (MS) likely results from an imbalance between regulatory and inflammatory immune processes. CD39 is an ectoenzyme that cleaves ATP to AMP and has been suggested as a novel regulatory T cells (Treg) marker. As ATP has numerous proinflammatory effects, its degradation by...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239031/ https://www.ncbi.nlm.nih.gov/pubmed/25411844 http://dx.doi.org/10.1371/journal.pone.0113025 |