Macrophage Migration Inhibitory Factor Deficiency Ameliorates High-Fat Diet Induced Insulin Resistance in Mice with Reduced Adipose Inflammation and Hepatic Steatosis

Macrophage infiltration is a critical determinant of high-fat diet induced adipose tissue inflammation and insulin resistance. The precise mechanisms underpinning the initiation of macrophage recruitment and activation are unclear. Macrophage migration inhibitory factor (MIF), a pro-inflammatory cyt...

Descripción completa

Detalles Bibliográficos
Autores principales: Finucane, Orla M., Reynolds, Clare M., McGillicuddy, Fiona C., Harford, Karen A., Morrison, Martine, Baugh, John, Roche, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239060/
https://www.ncbi.nlm.nih.gov/pubmed/25412423
http://dx.doi.org/10.1371/journal.pone.0113369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239060/
https://www.ncbi.nlm.nih.gov/pubmed/25412423
http://dx.doi.org/10.1371/journal.pone.0113369

Ejemplares similares