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Macrophage Migration Inhibitory Factor Deficiency Ameliorates High-Fat Diet Induced Insulin Resistance in Mice with Reduced Adipose Inflammation and Hepatic Steatosis

Macrophage infiltration is a critical determinant of high-fat diet induced adipose tissue inflammation and insulin resistance. The precise mechanisms underpinning the initiation of macrophage recruitment and activation are unclear. Macrophage migration inhibitory factor (MIF), a pro-inflammatory cyt...

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Detalles Bibliográficos
Autores principales:	Finucane, Orla M., Reynolds, Clare M., McGillicuddy, Fiona C., Harford, Karen A., Morrison, Martine, Baugh, John, Roche, Helen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239060/ https://www.ncbi.nlm.nih.gov/pubmed/25412423 http://dx.doi.org/10.1371/journal.pone.0113369

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