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Trehalose, an mTOR Independent Autophagy Inducer, Alleviates Human Podocyte Injury after Puromycin Aminonucleoside Treatment

Glomerular diseases are commonly characterized by podocyte injury including apoptosis, actin cytoskeleton rearrangement and detachment. However, the strategies for preventing podocyte damage remain insufficient. Recently autophagy has been regarded as a vital cytoprotective mechanism for keeping pod...

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Detalles Bibliográficos
Autores principales: Kang, Yu-Lin, Saleem, Moin Ahson, Chan, Kwok Wah, Yung, Benjamin Yat-Ming, Law, Helen Ka-Wai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239098/
https://www.ncbi.nlm.nih.gov/pubmed/25412249
http://dx.doi.org/10.1371/journal.pone.0113520