Dramatic response to dabrafenib and trametinib combination in a BRAF V600E-mutated cholangiocarcinoma: implementation of a molecular tumour board and next-generation sequencing for personalized medicine

This is the case of a 47-year-old woman diagnosed with chemotherapy and radiation-refractory BRAF V600E mutant, poorly differentiated intrahepatic cholangiocarcinoma (ICC), with multiple metastatic lesions within the liver, lungs, pleura, and bone, stage IV. Discussion of her malignancy’s next-gener...

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Detalles Bibliográficos
Autores principales: Loaiza-Bonilla, Arturo, Clayton, Erica, Furth, Emma, O’Hara, Mark, Morrissette, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239128/
https://www.ncbi.nlm.nih.gov/pubmed/25435907
http://dx.doi.org/10.3332/ecancer.2014.479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239128/
https://www.ncbi.nlm.nih.gov/pubmed/25435907
http://dx.doi.org/10.3332/ecancer.2014.479

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