Recombination–deletion between homologous cassettes in retrovirus is suppressed via a strategy of degenerate codon substitution

Transduction and expression procedures in gene therapy protocols may optimally transfer more than a single gene to correct a defect and/or transmit new functions to recipient cells or organisms. This may be accomplished by transduction with two (or more) vectors, or, more efficiently, in a single ve...

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Detalles Bibliográficos
Autores principales: Im, Eung Jun, Bais, Anthony J, Yang, Wen, Ma, Qiangzhong, Guo, Xiuyang, Sepe, Steven M, Junghans, Richard P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239131/
https://www.ncbi.nlm.nih.gov/pubmed/25419532
http://dx.doi.org/10.1038/mtm.2014.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239131/
https://www.ncbi.nlm.nih.gov/pubmed/25419532
http://dx.doi.org/10.1038/mtm.2014.22

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