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Recombination–deletion between homologous cassettes in retrovirus is suppressed via a strategy of degenerate codon substitution
Transduction and expression procedures in gene therapy protocols may optimally transfer more than a single gene to correct a defect and/or transmit new functions to recipient cells or organisms. This may be accomplished by transduction with two (or more) vectors, or, more efficiently, in a single ve...
Autores principales: | Im, Eung Jun, Bais, Anthony J, Yang, Wen, Ma, Qiangzhong, Guo, Xiuyang, Sepe, Steven M, Junghans, Richard P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239131/ https://www.ncbi.nlm.nih.gov/pubmed/25419532 http://dx.doi.org/10.1038/mtm.2014.22 |
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