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A validated miRNA profile predicts response to therapy in esophageal adenocarcinoma

BACKGROUND: In the current study we present a validated miRNA signature to predict pathologic complete response (pCR) to neoadjuvant chemoradiation in esophageal adenocarcinoma. METHODS: Three patient cohorts (discovery, n = 10; model, n = 43; and validation, n = 65) with locally advanced esophageal...

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Detalles Bibliográficos
Autores principales: Skinner, Heath D, Lee, Jeffrey H, Bhutani, Manoop S, Weston, Brian, Hofstetter, Wayne, Komaki, Ritsuko, Shiozaki, Hironori, Wadhwa, Roopma, Sudo, Kazuki, Elimova, Elena, Song, Shumei, Ye, Yuanqing, Huang, Maosheng, Ajani, Jaffer, Wu, Xifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239178/
https://www.ncbi.nlm.nih.gov/pubmed/25091571
http://dx.doi.org/10.1002/cncr.28911