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A Cross-chiral RNA Polymerase Ribozyme

Thirty years ago it was shown that the non-enzymatic, template-directed polymerization of activated mononucleotides proceeds readily in a homochiral system, but is severely inhibited by the presence of the opposing enantiomer.(1) This finding poses a severe challenge for the spontaneous emergence of...

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Detalles Bibliográficos
Autores principales: Sczepanski, Jonathan T., Joyce, Gerald F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239201/
https://www.ncbi.nlm.nih.gov/pubmed/25363769
http://dx.doi.org/10.1038/nature13900