Quantitative investigation of the affinity of human respiratory syncytial virus phosphoprotein C-terminus binding to nucleocapsid protein

BACKGROUND: There are no approved small molecule drug therapies for human respiratory syncytial virus (hRSV), a cause of morbidity and mortality in at-risk newborns, the immunocompromised, and the elderly. We have investigated as a potential novel hRSV drug target the protein-protein interaction bet...

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Detalles Bibliográficos
Autores principales: Shapiro, Adam B, Gao, Ning, O’Connell, Nichole, Hu, Jun, Thresher, Jason, Gu, Rong-Fang, Overman, Ross, Hardern, Ian M, Sproat, Graham G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239318/
https://www.ncbi.nlm.nih.gov/pubmed/25407889
http://dx.doi.org/10.1186/s12985-014-0191-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239318/
https://www.ncbi.nlm.nih.gov/pubmed/25407889
http://dx.doi.org/10.1186/s12985-014-0191-2

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