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Quantitative investigation of the affinity of human respiratory syncytial virus phosphoprotein C-terminus binding to nucleocapsid protein

BACKGROUND: There are no approved small molecule drug therapies for human respiratory syncytial virus (hRSV), a cause of morbidity and mortality in at-risk newborns, the immunocompromised, and the elderly. We have investigated as a potential novel hRSV drug target the protein-protein interaction bet...

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Detalles Bibliográficos
Autores principales:	Shapiro, Adam B, Gao, Ning, O’Connell, Nichole, Hu, Jun, Thresher, Jason, Gu, Rong-Fang, Overman, Ross, Hardern, Ian M, Sproat, Graham G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239318/ https://www.ncbi.nlm.nih.gov/pubmed/25407889 http://dx.doi.org/10.1186/s12985-014-0191-2

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