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Decreased EAAT2 protein expression in the essential tremor cerebellar cortex

Genetic polymorphisms in Solute carrier family 1 (glial high affinity glutamate transporter), member 2 (SLC1A2) have been linked with essential tremor. SLC1A2 encodes excitatory amino acid transporter type 2 (EAAT2), which clears glutamate from the synaptic cleft. One postulated mechanism for essent...

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Detalles Bibliográficos
Autores principales: Lee, Michelle, Cheng, Melody M, Lin, Chi-Ying, Louis, Elan D, Faust, Phyllis L, Kuo, Sheng-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239402/
https://www.ncbi.nlm.nih.gov/pubmed/25391854
http://dx.doi.org/10.1186/s40478-014-0157-z