Cargando…

Structural basis for extracellular cis and trans RPTPσ signal competition in synaptogenesis

Receptor protein tyrosine phosphatase sigma (RPTPσ) regulates neuronal extension and acts as a presynaptic nexus for multiple protein and proteoglycan interactions during synaptogenesis. Unknown mechanisms govern the shift in RPTPσ function, from outgrowth promotion to synaptic organization. Here, w...

Descripción completa

Detalles Bibliográficos
Autores principales: Coles, Charlotte H., Mitakidis, Nikolaos, Zhang, Peng, Elegheert, Jonathan, Lu, Weixian, Stoker, Andrew W., Nakagawa, Terunaga, Craig, Ann Marie, Jones, E. Yvonne, Aricescu, A. Radu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239663/
https://www.ncbi.nlm.nih.gov/pubmed/25385546
http://dx.doi.org/10.1038/ncomms6209