Open adjacencies and k-breaks: detecting simultaneous rearrangements in cancer genomes

BACKGROUND: The evolution of a cancer genome has traditionally been described as a sequential accumulation of mutations - including chromosomal rearrangements - over a period of time. Recent research suggests, however, that numerous rearrangements may be acquired simultaneously during a single catac...

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Detalles Bibliográficos
Autores principales: Weinreb, Caleb, Oesper, Layla, Raphael, Benjamin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239675/
https://www.ncbi.nlm.nih.gov/pubmed/25572114
http://dx.doi.org/10.1186/1471-2164-15-S6-S4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239675/
https://www.ncbi.nlm.nih.gov/pubmed/25572114
http://dx.doi.org/10.1186/1471-2164-15-S6-S4

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