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Open adjacencies and k-breaks: detecting simultaneous rearrangements in cancer genomes
BACKGROUND: The evolution of a cancer genome has traditionally been described as a sequential accumulation of mutations - including chromosomal rearrangements - over a period of time. Recent research suggests, however, that numerous rearrangements may be acquired simultaneously during a single catac...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239675/ https://www.ncbi.nlm.nih.gov/pubmed/25572114 http://dx.doi.org/10.1186/1471-2164-15-S6-S4 |