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A Soft Sensor for Bioprocess Control Based on Sequential Filtering of Metabolic Heat Signals

Soft sensors are the combination of robust on-line sensor signals with mathematical models for deriving additional process information. Here, we apply this principle to a microbial recombinant protein production process in a bioreactor by exploiting bio-calorimetric methodology. Temperature sensor s...

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Detalles Bibliográficos
Autores principales: Paulsson, Dan, Gustavsson, Robert, Mandenius, Carl-Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239934/
https://www.ncbi.nlm.nih.gov/pubmed/25264951
http://dx.doi.org/10.3390/s141017864