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A Soft Sensor for Bioprocess Control Based on Sequential Filtering of Metabolic Heat Signals
Soft sensors are the combination of robust on-line sensor signals with mathematical models for deriving additional process information. Here, we apply this principle to a microbial recombinant protein production process in a bioreactor by exploiting bio-calorimetric methodology. Temperature sensor s...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239934/ https://www.ncbi.nlm.nih.gov/pubmed/25264951 http://dx.doi.org/10.3390/s141017864 |