Bridging the gap: a review of dose investigations in paediatric investigation plans

AIMS: In the EU, development of new medicines for children should follow a prospectively agreed paediatric investigation plan (PIP). Finding the right dose for children is crucial but challenging due to the variability of pharmacokinetics across age groups and the limited sample sizes available. We...

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Detalles Bibliográficos
Autores principales: Hampson, Lisa V, Herold, Ralf, Posch, Martin, Saperia, Julia, Whitehead, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Methods in Clinical Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239983/
https://www.ncbi.nlm.nih.gov/pubmed/24720849
http://dx.doi.org/10.1111/bcp.12402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239983/
https://www.ncbi.nlm.nih.gov/pubmed/24720849
http://dx.doi.org/10.1111/bcp.12402

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