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Proteomic analysis of formalin-fixed paraffin-embedded glomeruli suggests depletion of glomerular filtration barrier proteins in two-kidney, one-clip hypertensive rats

BACKGROUND: It is well known that hypertension may cause glomerular damage, but the molecular mechanisms involved are still incompletely understood. METHODS: In the present study, we used formalin-fixed paraffin-embedded (FFPE) tissue to investigate changes in the glomerular proteome in the non-clip...

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Detalles Bibliográficos
Autores principales: Finne, Kenneth, Vethe, Heidrun, Skogstrand, Trude, Leh, Sabine, Dahl, Tone D., Tenstad, Olav, Berven, Frode S., Reed, Rolf K., Vikse, Bjørn Egil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240179/
https://www.ncbi.nlm.nih.gov/pubmed/25129444
http://dx.doi.org/10.1093/ndt/gfu268